Timing of tracheotomy in ICU patients: a systematic review of randomized controlled trials Critical Care 2015;19:424...

Comparative Effectiveness of Pharmacologic Interventions for Knee Osteoarthritis Ann Intern Med. 2015;162:46-54. 昨年にでたNMA: network...

The Efficacy of Earplugs as a Sleep Hygiene Strategy for Reducing Delirium in the ICU: A Systematic Review and Meta-Analysis Critical...

Frequency of discrepancies in retracted clinical trial reports versus unretracted reports: blinded case-control study BMJ 2015;351:h4708...

Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone JAMA Intern Med. 2015;175(11):1839-1847. 台湾からのcase...

Early Dual Versus Mono Antiplatelet Therapy for Acute Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack An Updated...

High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure N Engl J Med 2015;372:2185-96. a multicenter, open-label...

A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor. Arch Neurol. 1999 Apr;56(4):475-80....

Comprehensive geriatric care for patients with hip fractures: a prospective, randomised, controlled trial Lancet 2015; 385: 1623–33...

Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial Prim Care...

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes IMPROVE-IT試験 DOI: 10.1056/NEJMoa1410489 online first double-blind,...

Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults 背景 肺炎球菌多糖体結合ワクチンは乳児の肺炎球菌感染症を予防するが，65...

Effectiveness of Cranberry capsules to prevent uninary tract infections in vulnerable older persons: A double-blind randomized...

2013年のホノルルショック以来，デバイスやstudyデザインの見直しなどで血管内治療の有用性が示されつつあります． MR CLEAN (NEJM 2015; 372: 11-20) pragmatic, phase 3, multicenter clinical...